Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 7/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955940 | 1.00 | FFAR1 (0.35) | FFAR1GPR88GPBAR1CYP4F2CYP4A11 | |
| SCHEMBL15956910 | 0.88 | FFAR1 (0.41) | FFAR1GPR88GPBAR1CYP4F2CYP4A11 | |
| SCHEMBL15955822 | 0.80 | FFAR1 (0.33) | FFAR1GPR88GPBAR1 | |
| SCHEMBL15955827 | 0.80 | FFAR1 (0.33) | FFAR1GPR88GPBAR1 | |
| SCHEMBL15955604 | 0.75 | PLA2G2A (0.48) | — | |
| SCHEMBL17124422 | 0.75 | DAO (0.43) | CYP4F2CYP4A11 | |
| SCHEMBL208982 | 0.74 | KDM4E (0.43) | FFAR1 | |
| SCHEMBL16246962 | 0.73 | THRA (0.41) | GPR88GPBAR1CYP4F2CYP4A11 | |
| SCHEMBL9493362 | 0.70 | ALDH1A1 (0.40) | — | |
| SCHEMBL3567621 | 0.67 | PTGS2 (0.39) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10077233-B2 | Poly-cyanostilbene macrocycles | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-18 | — | — | US | disclosed |
| US-20170313652-A1 | Poly-Cyanostilbene Macrocycles | NATIONAL SCIENCE FOUNDATION | 2017-11-02 | — | — | US | disclosed |
| US-20170313652-A1 | Poly-Cyanostilbene Macrocycles | NATIONAL SCIENCE FOUNDATION | 2017-11-02 | — | — | US | disclosed |
| US-20170313652-A1 | Poly-Cyanostilbene Macrocycles | NATIONAL SCIENCE FOUNDATION | 2017-11-02 | — | — | US | disclosed |
| US-9701621-B2 | Poly-cyanostilbene macrocycles | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701621-B2 | Poly-cyanostilbene macrocycles | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701621-B2 | Poly-cyanostilbene macrocycles | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2017-07-11 | — | — | US | disclosed |
| US-20150376122-A1 | Poly-Cyanostilbene Macrocycles | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-12-31 | — | — | US | disclosed |
| US-20150376122-A1 | Poly-Cyanostilbene Macrocycles | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-12-31 | — | — | US | disclosed |
| US-20150376122-A1 | Poly-Cyanostilbene Macrocycles | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-12-31 | — | — | US | disclosed |
| WO-2014127171-A1 | POLY-CYANOSTILBENE MACROCYCLES | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2014-08-21 | — | — | WO | disclosed |
| WO-2014127171-A1 | POLY-CYANOSTILBENE MACROCYCLES | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2014-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376122-A1 | Poly-Cyanostilbene Macrocycles | PCBP1, HCCS, ACVR2B | FFAR1 4172/4885GPR88 2636/4885GPBAR1 1530/4885 |
| US-20170313652-A1 | Poly-Cyanostilbene Macrocycles | PCBP1, HCCS, ACVR2B | FFAR1 4172/4885GPR88 2636/4885GPBAR1 1530/4885 |
| US-10077233-B2 | Poly-cyanostilbene macrocycles | PCBP1, HCCS, ACVR2B | FFAR1 4172/4885GPR88 2636/4885GPBAR1 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.