SCHEMBL159572

SCHEMBL159572

[O-]c1c(Cl)cc(-[n+]2c(-c3ccccc3)cc(-c3ccccc3)cc2-c2ccccc2)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.59
RAB9A P51151 9/20 0.59
NTSR1 P30989 3/20 0.59
HTT P42858 3/20 0.59
MAPK1 P28482 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
KDM4E B2RXH2 2/20 0.59
UHRF1 Q96T88 1/20 0.59
NR2F2 P24468 1/20 0.55
RAD52 P43351 1/20 0.55
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
MAPT P10636 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
LMNA P02545 1/20 0.51
NPY1R P25929 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CA2 P00918 3/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30466628 0.86 NPC1 (0.58) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL11988997 0.83 RAB9A (0.55) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL805082 0.81 NPC1 (0.77) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL158977 0.81 NPC1 (0.66) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL11533950 0.77 NPC1 (0.84) NPC1RAB9ANTSR1HTTMAPK1
Water SCHEMBL29507345 0.77 NPC1 (0.70) NPC1RAB9ANTSR1HTTMAPK1
Perchlorate SCHEMBL11536227 0.74 NPC1 (1.00) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL4250857 0.73 RAB9A (0.87) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL17971504 0.73 NPC1 (0.65) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL17971498 0.73 NPC1 (0.65) NPC1RAB9ANTSR1HTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557182-B2 Site selectively tagged and templated molecularly imprinted polymers for sensor applications THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2013-10-15 US claimed
US-8377717-B2 Site selectively tagged and templated molecularly imprinted polymers for sensor applications THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2013-02-19 US claimed
WO-2012031128-A2 MICROORGANISM IMPRINTED POLYMERS WITH INTEGRATED EMISSION SITES, AND METHODS OF MAKING AND USING SAME THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2012-03-08 WO claimed
JP-4804361-B2 2011-11-02 JP claimed
JP-4682153-B2 2011-05-11 JP claimed
US-20100233828-A1 Site Selectively Tagged and Templated Molecularly Imprinted Polymers for Sensor Applications RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE (US) 2010-09-16 US claimed
US-7598087-B2 Protein imprinted polymers with integrated emission sites THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2009-10-06 US claimed
EP-1706728-A4 PROTEIN IMPRINTED POLYMERS WITH INTEGRATED EMISSION SITES UNIV NEW YORK STATE RES FOUND (US) 2008-03-12 EP claimed
EP-1706728-A1 PROTEIN IMPRINTED POLYMERS WITH INTEGRATED EMISSION SITES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2006-10-04 EP claimed
EP-1699832-A2 SITE SELECTIVELY TAGGED AND TEMPLATED MOLECULARLY IMPRINTED POLYMERS FOR SENSOR APPLICATIONS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2006-09-13 EP claimed
US-20050227258-A1 Site selectively tagged and templated molecularly imprinted polymers for sensor applications NATIONAL SCIENCE FOUNDATION 2005-10-13 US claimed
US-20050214876-A1 Protein imprinted polymers with integrated emission sites NATIONAL SCIENCE FOUNDATION 2005-09-29 US claimed
WO-2005068980-A1 PROTEIN IMPRINTED POLYMERS WITH INTEGRATED EMISSION SITES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2005-07-28 WO claimed
WO-2005056613-A2 SITE SELECTIVELY TAGGED AND TEMPLATED MOLECULARLY IMPRINTED POLYMERS FOR SENSOR APPLICATIONS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2005-06-23 WO claimed
US-11884956-B2 Methods for detecting mycobacteria with solvatochromic dye conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-01-30 US disclosed
US-20190169671-A1 Methods for Detecting Mycobacteria with Solvatochromic Dye Conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-06-06 US disclosed
EP-3491144-A1 METHODS FOR DETECTING MYCOBACTERIA WITH SOLVATOCHROMIC DYE CONJUGATES The Board of Trustees of the Leland Stanford Junior University (US) 2019-06-05 EP disclosed
US-20050214876-A1 Protein imprinted polymers with integrated emission sites NATIONAL SCIENCE FOUNDATION 2005-09-29 US disclosed
WO-2005068980-A1 PROTEIN IMPRINTED POLYMERS WITH INTEGRATED EMISSION SITES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2005-07-28 WO disclosed
WO-2005056613-A2 SITE SELECTIVELY TAGGED AND TEMPLATED MOLECULARLY IMPRINTED POLYMERS FOR SENSOR APPLICATIONS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2005-06-23 WO disclosed