Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615422 | 0.85 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1GAAPOLB | |
| SCHEMBL23601591 | 0.85 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1GAAPOLB | |
| SCHEMBL21501052 | 0.85 | HSD11B1 (0.67) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL19597541 | 0.85 | ALDH1A1 (0.70) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL19597540 | 0.85 | ALDH1A1 (0.70) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL21501050 | 0.83 | ALDH1A1 (0.56) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL21501014 | 0.83 | ALDH1A1 (0.56) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL21501019 | 0.83 | ALDH1A1 (0.56) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL1597751 | 0.83 | ALDH1A1 (0.57) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL17446827 | 0.80 | KMT2A (0.46) | KMT2AMEN1ALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919515-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2011-04-05 | — | — | US | disclosed |
| US-7919515-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2011-04-05 | — | — | US | disclosed |
| US-7919515-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2011-04-05 | — | — | US | disclosed |
| US-7629370-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2009-12-08 | — | — | US | disclosed |
| US-7629370-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2009-12-08 | — | — | US | disclosed |
| EP-1874745-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA RECEPTOR LIGANDS | Adamed SP. Z O.O. (PL) | 2008-01-09 | — | — | EP | disclosed |
| US-7312338-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-12-25 | — | — | US | disclosed |
| US-7312338-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-12-25 | — | — | US | disclosed |
| US-7312338-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-12-25 | — | — | US | disclosed |
| US-7309791-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z.O.O (PL) | 2007-12-18 | — | — | US | disclosed |
| US-7220766-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-05-22 | — | — | US | disclosed |
| US-7220766-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-05-22 | — | — | US | disclosed |
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-04-19 | — | — | US | disclosed |
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-04-19 | — | — | US | disclosed |
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-04-19 | — | — | US | disclosed |
| WO-2006077206-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA REZEPTOR LIGANDEN | ADAMED SP. Z O.O. (PL) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006077217-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | ADAMED SP. Z O.O. (PL) | 2006-07-27 | — | — | WO | disclosed |
| US-20060160870-A1 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2006-07-20 | — | — | US | disclosed |
| US-20060160868-A1 | 3-Phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2006-07-20 | — | — | US | disclosed |
| WO-2006067086-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | ADAMED SP. Z O.O. (PL) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | PPARA, PPARD, PPARG | KMT2A 3855/4885MEN1 4733/4885NPC1 568/4885 |
| US-20060160870-A1 | 3-phenylpropionic acid derivatives | PPARA, PPARG, PPARD | KMT2A 4042/4885MEN1 4724/4885NPC1 582/4885 |
| US-20060160868-A1 | 3-Phenylpropionic acid derivatives | PPARA, PPARG, PPARD | KMT2A 4155/4885MEN1 4549/4885NPC1 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.