SCHEMBL15960871

SCHEMBL15960871

Cc1ccc(C(c2ccc(C)cc2)c2ccc3c(c2)C(=O)c2cc(C)cc(C)c2C3)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.43
ELANE P08246 1/20 0.35
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
BCL2 P10415 1/20 0.31
MCL1 Q07820 1/20 0.31
ACHE P22303 2/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PARP1 P09874 1/20 0.31
PARP10 Q53GL7 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
RAPGEF4 Q8WZA2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6906767 0.75 MAOA (0.55) METAP1ELANEMEN1KMT2AMAOA
SCHEMBL23272970 0.72 METAP1 (0.46) METAP1MEN1KMT2AMAOAMAOB
SCHEMBL1609651 0.70 METAP1 (0.71) METAP1ELANEMEN1KMT2AMAOA
SCHEMBL6056920 0.69 METAP1 (0.69) METAP1ELANEMEN1KMT2AMAOA
SCHEMBL10694839 0.67 AKT1 (0.43) METAP1ELANEMEN1KMT2AMAOA
SCHEMBL6056983 0.67 METAP1 (0.67) METAP1ELANEMEN1KMT2AMAOA
SCHEMBL1611036 0.66 METAP1 (0.65) METAP1ELANEMEN1KMT2AMAOA
SCHEMBL6277979 0.65 PNMT (0.41) MEN1KMT2AMAOAACHEGAA
SCHEMBL27456260 0.65 METAP1 (0.62) METAP1ELANEMEN1KMT2AMAOA
SCHEMBL1512741 0.64 METAP1 (0.67) METAP1ELANEMEN1KMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140235747-A1 LIQUID RADIATION CURABLE RESINS CAPABLE OF CURING INTO LAYERS WITH SELECTIVE VISUAL EFFECTS AND METHODS FOR THE USE THEREOF DSM IP ASSETS B.V. (NL) 2014-08-21 US disclosed