Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16369092 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL10110367 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL22591175 | 0.70 | THRB (0.36) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL15964123 | 0.69 | — | — | |
| SCHEMBL14715973 | 0.69 | SMN1; SMN2 (0.39) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL15964134 | 0.68 | — | — | |
| SCHEMBL22538631 | 0.68 | THRB (0.40) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL18253536 | 0.64 | HMGCR (0.43) | SMN1; SMN2ALOX15 | |
| SCHEMBL11955197 | 0.63 | THRB (0.45) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL9618778 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235819-A1 | Deuterated Cyclosporine Analogs and Methods of Making the Same | AURINIA PHARMACEUTICALS, INC. (CA) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235819-A1 | Deuterated Cyclosporine Analogs and Methods of Making the Same | GOT2, CS, DLD | SMN1; SMN2 2116/4885THRB 3621/4885ALOX15 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.