SCHEMBL15964210

SCHEMBL15964210

O=C(NNc1ccc(NS(=O)(=O)c2cccc(-n3nnnc3S)c2)cc1)C(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 3/20 0.36
NFE2L2 Q16236 3/20 0.36
KMT2A Q03164 2/20 0.35
PKM P14618 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GFER P55789 1/20 0.35
PMM2 O15305 1/20 0.35
MPI P34949 1/20 0.35
PHOSPHO1 Q8TCT1 1/20 0.35
DDX3X O00571 1/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13297717 0.87 MAPT (0.41) KEAP1NFE2L2PKML3MBTL1GFER
SCHEMBL14093865 0.84 MAPT (0.36) KEAP1NFE2L2PKML3MBTL1GFER
SCHEMBL8988112 0.81 PMM2 (0.35) KEAP1NFE2L2KMT2APKMGFER
SCHEMBL8650519 0.76 IDH1 (0.40) KEAP1NFE2L2KMT2APKML3MBTL1
SCHEMBL9178869 0.74 HTR6 (0.51) KEAP1NFE2L2KMT2APKML3MBTL1
SCHEMBL4591741 0.71 LMNA (0.43) KEAP1NFE2L2KMT2APKML3MBTL1
SCHEMBL278418 0.71 LMNA (0.43) KEAP1NFE2L2KMT2APKML3MBTL1
SCHEMBL31457351 0.71 LMNA (0.43) KEAP1NFE2L2KMT2APKML3MBTL1
SCHEMBL29672419 0.71 LMNA (0.43) KEAP1NFE2L2KMT2APKML3MBTL1
SCHEMBL1156164 0.70 LMNA (0.43) KMT2APKML3MBTL1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140234760-A1 TRANSLUCENT ELECTROMAGNETIC SHIELD FILM, PRODUCING METHOD THEREFOR AND EMULSIFIER FUJIFILM CORPORATION (JP) 2014-08-21 US disclosed
US-20140234760-A1 TRANSLUCENT ELECTROMAGNETIC SHIELD FILM, PRODUCING METHOD THEREFOR AND EMULSIFIER FUJIFILM CORPORATION (JP) 2014-08-21 US disclosed