SCHEMBL8988112

SCHEMBL8988112

O=CNNc1ccc(NS(=O)(=O)c2cccc(-n3nnnc3S)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PMM2 O15305 1/20 0.35
MPI P34949 1/20 0.35
PHOSPHO1 Q8TCT1 1/20 0.35
PGR P06401 5/20 0.34
PKM P14618 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
POLB P06746 1/20 0.34
TP53 P04637 1/20 0.34
NPY5R Q15761 1/20 0.34
KEAP1 Q14145 2/20 0.33
NFE2L2 Q16236 2/20 0.33
EP300 Q09472 1/20 0.33
HPGD P15428 1/20 0.33
GFER P55789 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8650519 0.90 IDH1 (0.40) PKMMEN1KMT2ALMNAMAPT
SCHEMBL13297717 0.83 MAPT (0.41) PKMMAPTPOLBTP53KEAP1
SCHEMBL15964210 0.81 KEAP1 (0.36) PMM2MPIPHOSPHO1PGRPKM
SCHEMBL14093865 0.80 MAPT (0.36) PGRPKMLMNAMAPTPOLB
SCHEMBL9178869 0.78 HTR6 (0.51) PKMMEN1KMT2AKEAP1NFE2L2
SCHEMBL8967607 0.77 CNR1 (0.39) MEN1KMT2ALMNAMAPT
SCHEMBL8967579 0.77 MEN1 (0.45) MEN1KMT2ALMNAPOLBTP53
SCHEMBL278418 0.72 LMNA (0.43) PKMKMT2ALMNAMAPTPOLB
SCHEMBL4591741 0.72 LMNA (0.43) PKMKMT2ALMNAMAPTPOLB
SCHEMBL8740829 0.72 LMNA (0.43) PKMKMT2ALMNAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1818718-A2 Photothermographic material and method of thermal development of the same Fuji Photo Film Co., Ltd. (JP) 2007-08-15 EP disclosed
EP-0393477-B1 Direct positive photosensitive material FUJI PHOTO FILM CO LTD (JP) 1996-07-03 EP disclosed
EP-0355818-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-05-10 EP disclosed
EP-0358170-B1 Direct positive photographic materials FUJI PHOTO FILM CO LTD (JP) 1994-08-24 EP disclosed
EP-0322702-B1 Direct positive photographic materials FUJI PHOTO FILM CO LTD (JP) 1994-07-20 EP disclosed
US-5306608-A Non-pre-fogged internal latent image type silver halide grains of a core/shell structure FUJI PHOTO FILM CO., LTD. (JP) 1994-04-26 US disclosed
EP-0283041-B1 DIRECT POSITIVE SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD FOR FORMING DIRECT POSITIVE IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1992-10-07 EP disclosed
EP-0286062-B1 SILVER HALIDE PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1992-07-15 EP disclosed
US-H972-H Direct positive color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US disclosed
US-4996137-A Developing exposed material containing emulsion layer with hexagonal tabular silver bromide core/shell grains FUJI PHOTO FILM CO., LTD. (JP) 1991-02-26 US disclosed
US-4956267-A PRESERVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-09-11 US disclosed
US-4952483-A NOVEL HYDRAZINE NUCLEATING AGENTS AND ACCELERATORS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-28 US disclosed
US-4945033-A Direct positive photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-07-31 US disclosed
US-4925777-A Direct positives FUJI PHOTO FILM CO., LTD. (JP) 1990-05-15 US disclosed
EP-0360289-A2 Positive working silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-03-28 EP disclosed
EP-0355818-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-02-28 EP disclosed
EP-0322702-A2 Direct positive photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0286062-A1 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-10-12 EP disclosed
EP-0285010-A2 Method for forming a direct positive color image FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP disclosed
EP-0283041-A1 Direct positive silver halide photosensitive material and method for forming direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 EP disclosed