SCHEMBL15964348

SCHEMBL15964348

CNCn1c2ccccc2c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
CYP2C19 P33261 1/20 0.56
CYP19A1 P11511 1/20 0.48
BACE1 P56817 2/20 0.47
GPR3 P46089 1/20 0.46
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.45
HDAC6 Q9UBN7 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
HBB P68871 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
FABP4 P15090 2/20 0.42
FABP5 Q01469 2/20 0.42
FABP3 P05413 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11710300 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP19A1BACE1GPR3
SCHEMBL11712442 0.75 FABP4 (0.51) HDAC6FABP4FABP5PGRRORA
SCHEMBL17928418 0.75 CYP1A2 (0.48) CYP1A2CYP2C19CYP19A1BACE1GPR3
SCHEMBL12439957 0.73 GPR3 (0.52) CYP1A2CYP2C19CYP19A1BACE1GPR3
SCHEMBL29360167 0.73 ALDH1A1 (0.75) CYP1A2CYP2C19CYP19A1BACE1GPR3
SCHEMBL29963695 0.73 ALDH1A1 (0.75) CYP1A2CYP2C19CYP19A1BACE1GPR3
SCHEMBL151563 0.73 ALDH1A1 (0.75) CYP1A2CYP2C19CYP19A1BACE1GPR3
SCHEMBL25594457 0.72 MAOA (0.55) HDAC6FABP4FABP5
SCHEMBL6007889 0.72 CYP1A2 (0.50) CYP1A2CYP2C19CYP19A1BACE1GPR3
SCHEMBL6008130 0.72 CYP1A2 (0.50) CYP1A2CYP2C19CYP19A1BACE1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed