Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 5/20 | 0.36 |
| ▸ | RXRA | P19793 | 4/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582897 | 0.92 | ALDH1A1 (0.59) | GABRA1GABRB2ALDH1A1ALOX15MEN1 | |
| SCHEMBL11094902 | 0.82 | ALDH1A1 (0.50) | GABRA1GABRB2ALDH1A1ALOX15MEN1 | |
| SCHEMBL10929633 | 0.82 | ALDH1A1 (0.50) | GABRA1GABRB2ALDH1A1ALOX15POLB | |
| SCHEMBL11811353 | 0.79 | ALDH1A1 (0.65) | ALDH1A1ALOX15POLBHPGDHSD17B10 | |
| SCHEMBL11572922 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ALOX15POLBRXRBRXRA | |
| SCHEMBL2969176 | 0.77 | ALDH1A1 (0.70) | GABRA1GABRB2ALDH1A1ALOX15RXRB | |
| SCHEMBL11072941 | 0.77 | ALDH1A1 (0.45) | GABRA1GABRB2ALDH1A1ALOX15 | |
| SCHEMBL93161 | 0.76 | GABRA1 (0.69) | GABRA1GABRB2ALDH1A1ALOX15POLB | |
| SCHEMBL44978 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1ALOX15POLB | |
| SCHEMBL3262455 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1ALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889926-B2 | Method for the synthesis of low cost initiators for telechelic polyisobutylenes | THE UNIVERSITY OF AKRON (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140235905-A1 | METHOD FOR THE SYNTHESIS OF LOW COST INITIATORS FOR TELECHELIC POLYISOBUTYLENES | THE UNIVERSITY OF AKRON (US) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235905-A1 | METHOD FOR THE SYNTHESIS OF LOW COST INITIATORS FOR TELECHELIC POLYISOBUTYLENES | TERT, TBCB, CAT | GABRA1 1456/4885GABRB2 606/4885ALDH1A1 972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.