Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HK2 | P52789 | 5/20 | 0.48 |
| ▸ | HK1 | P19367 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142537 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL14620999 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL5160455 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL15966251 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL14653772 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL15966275 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL14520986 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL5158214 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL22166026 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL5160461 | 1.00 | PYGB (0.66) | PYGBKDM4ELMNACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181607-A1 | THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION | The University of the Regents of California (US) | 2023-06-15 | — | — | US | disclosed |
| US-20180111955-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-04-26 | — | — | US | disclosed |
| US-9856283-B2 | Thiosaccharide mucolytic agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170204444-A9 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170016040-A1 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-19 | — | — | US | disclosed |
| US-9290530-B2 | Chemoenzymatic synthesis of heparin and heparan sulfate analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-22 | — | — | US | disclosed |
| US-20160060284-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-03 | — | — | US | disclosed |
| US-20140235575-A1 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235575-A1 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | HPSE, ENGASE, GALE | PYGB 898/4885KDM4E 1727/4885LMNA 4542/4885 |
| US-20180111955-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | MUC1, TREH, FUT6 | PYGB 3833/4885KDM4E 4766/4885LMNA 3808/4885 |
| US-20160060284-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | MUC1, TREH, FUT6 | PYGB 3833/4885KDM4E 4766/4885LMNA 3808/4885 |
| US-20230181607-A1 | THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION | TMPRSS4, ACE, ACE2 | PYGB 3255/4885KDM4E 4488/4885LMNA 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.