Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966916 | 0.84 | MAOB (0.43) | ALDH1A1MAPK1TSHRNPSR1HSD17B10 | |
| SCHEMBL9932139 | 0.73 | SMN1; SMN2 (0.47) | TSHRMAOBKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL24282130 | 0.70 | RAB9A (0.61) | ALDH1A1MAPK1HSD17B10ADORA2AADORA1 | |
| SCHEMBL6032763 | 0.68 | F7 (0.71) | F7F3ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL6031994 | 0.66 | F7 (0.54) | F7F3ALDH1A1MAPK1KDM4E | |
| SCHEMBL11645943 | 0.66 | RAB9A (0.58) | ALDH1A1MAPK1TSHRHSD17B10MAOB | |
| SCHEMBL12015945 | 0.65 | PTGES (0.60) | ALDH1A1MAPK1HSD17B10ADORA2AADORA1 | |
| SCHEMBL9867688 | 0.64 | SGMS2 (0.55) | ALDH1A1HSD17B10MAOBKDM4ESMN1; SMN2 | |
| SCHEMBL11642499 | 0.64 | MAOB (0.56) | ALDH1A1MAOBKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL14650242 | 0.64 | NPC1 (0.50) | ALDH1A1NPSR1HSD17B10MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523963-B1 | 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES AS EDG-1 AGONISTS | SANOFI SA (FR) | 2014-08-27 | — | — | EP | disclosed |