Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966899 | 0.84 | F7 (0.44) | MAOBHPGDKDM4ESMN1; SMN2CASP3 | |
| SCHEMBL9932139 | 0.76 | SMN1; SMN2 (0.47) | MAOBHPGDKDM4ESMN1; SMN2CASP3 | |
| SCHEMBL2224907 | 0.75 | S1PR1 (0.42) | HPGDKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11645943 | 0.69 | RAB9A (0.58) | MAOBHPGDKDM4ESMN1; SMN2CASP3 | |
| SCHEMBL23877677 | 0.69 | MAOB (0.47) | MAOBNTRK1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL18310041 | 0.68 | NTRK1 (0.56) | NTRK1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL11642499 | 0.67 | MAOB (0.56) | MAOBHPGDKDM4ESMN1; SMN2CASP3 | |
| SCHEMBL9867688 | 0.67 | SGMS2 (0.55) | MAOBHPGDKDM4ESMN1; SMN2CASP3 | |
| SCHEMBL6885681 | 0.67 | RAB9A (0.54) | NTRK1HPGDKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL14650242 | 0.67 | NPC1 (0.50) | MAOBHPGDKDM4ESMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523963-B1 | 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES AS EDG-1 AGONISTS | SANOFI SA (FR) | 2014-08-27 | — | — | EP | disclosed |