Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL27771912 | 0.77 | ALDH1A1 (0.37) | — | |
| Ether SCHEMBL9750502 | 0.77 | — | — | |
| SCHEMBL37015 | 0.77 | ALDH1A1 (0.33) | — | |
| Ether SCHEMBL27956860 | 0.74 | — | — | |
| Ether SCHEMBL861634 | 0.74 | — | — | |
| Ether SCHEMBL7679560 | 0.74 | ALDH1A1 (0.46) | — | |
| Ether SCHEMBL28723305 | 0.74 | ALDH1A1 (0.36) | — | |
| Ether SCHEMBL28410305 | 0.74 | ALDH1A1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL5712632 | 0.73 | ALDH1A1 (0.31) | — | |
| Ether SCHEMBL7738174 | 0.73 | LMNA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015378-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2026-01-15 | — | — | US | disclosed |
| US-12258368-B2 | Disulfide-linked reversible terminators | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2025-03-25 | — | — | US | disclosed |
| US-20220389049-A1 | REVERSIBLE TERMINATORS FOR DNA SEQUENCING AND METHODS OF USING THE SAME | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (VG) | 2022-12-08 | — | — | US | disclosed |
| US-20220048940-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2022-02-17 | — | — | US | disclosed |
| US-11180522-B2 | Disulfide-linked reversible terminators | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2021-11-23 | — | — | US | disclosed |
| EP-3856753-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | Centrillion Technology Holdings Corporation (KY) | 2021-08-04 | — | — | EP | disclosed |
| WO-2021067970-A1 | REVERSIBLE TERMINATORS FOR DNA SEQUENCING AND METHODS OF USING THE SAME | CENTRILLION TECHNOLOGIES, INC. (US) | 2021-04-08 | — | — | WO | disclosed |
| WO-2020069424-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGIES, INC. (US) | 2020-04-02 | — | — | WO | disclosed |
| EP-3091026-B1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECH HOLDINGS CORP (KY) | 2019-02-20 | — | — | EP | disclosed |
| US-10059986-B2 | Reversible terminator molecules and methods of their use | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (US) | 2018-08-28 | — | — | US | disclosed |
| US-20170218441-A1 | REVERSIBLE TERMINATOR MOLECULES AND METHODS OF THEIR USE | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (US) | 2017-08-03 | — | — | US | disclosed |
| US-9650406-B2 | Reversible terminator molecules and methods of their use | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (US) | 2017-05-16 | — | — | US | disclosed |
| US-20160355541-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2016-12-08 | — | — | US | disclosed |
| WO-2016182984-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2016-11-17 | — | — | WO | disclosed |
| EP-3091026-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | Centrillion Technology Holdings Corporation (KY) | 2016-11-09 | — | — | EP | disclosed |
| US-20140242579-A1 | REVERSIBLE TERMINATOR MOLECULES AND METHODS OF THEIR USE | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048940-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | RNGTT, NSUN2, NSUN3 | LMNA 3074/4885 |
| US-20220389049-A1 | REVERSIBLE TERMINATORS FOR DNA SEQUENCING AND METHODS OF USING THE SAME | RNGTT, NT5C3B, NSUN2 | LMNA 618/4885 |
| US-20260015378-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | RNGTT, NSUN2, NSUN3 | LMNA 369/4885 |
| US-11180522-B2 | Disulfide-linked reversible terminators | RNGTT, NSUN3, NSUN2 | LMNA 413/4885 |
| US-12258368-B2 | Disulfide-linked reversible terminators | RNGTT, NSUN2, NSUN3 | LMNA 3074/4885 |
| US-20160355541-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | RNGTT, NSUN2, NSUN3 | LMNA 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.