Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893121 | 1.00 | ACACB (0.39) | ACACBCYP3A4 | |
| SCHEMBL893582 | 0.85 | SLC6A3 (0.37) | CYP3A4 | |
| SCHEMBL4247931 | 0.83 | ACACB (0.41) | ACACBCYP3A4 | |
| SCHEMBL4247930 | 0.83 | ACACB (0.41) | ACACBCYP3A4 | |
| SCHEMBL893583 | 0.78 | GPR142 (0.43) | CYP3A4 | |
| SCHEMBL14119112 | 0.76 | CYP3A4 (0.43) | CYP3A4 | |
| SCHEMBL9943573 | 0.73 | CTRB1 (0.44) | ACACBCYP3A4 | |
| SCHEMBL9943572 | 0.73 | CTRB1 (0.44) | ACACBCYP3A4 | |
| SCHEMBL9943574 | 0.73 | CTRB1 (0.44) | ACACBCYP3A4 | |
| SCHEMBL4252268 | 0.72 | CYP3A4 (0.36) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243340-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | ABBVIE INC. (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243340-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | CYP3A43, CYP3A5, POR | ACACB 1446/4885CYP3A4 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.