Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 1.00 |
| ▸ | GSK3A | P49840 | 3/20 | 0.73 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.73 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.71 |
| ▸ | HINT1 | P49773 | 7/20 | 0.65 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | KRAS | P01116 | 1/20 | 0.56 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219707 | 0.88 | GSK3A (0.80) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL6551642 | 0.86 | PNP (0.75) | PNPGSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL9607792 | 0.83 | ABCB1 (1.00) | PNPGSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL4629734 | 0.83 | ABCB1 (1.00) | PNPGSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL611618 | 0.83 | ABCB1 (1.00) | PNPGSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL9605293 | 0.83 | ABCB1 (1.00) | PNPGSK3ARPS6KA3MAPK14ABCB1 | |
| Hydrochloric Acid SCHEMBL19666771 | 0.83 | ABCB1 (0.98) | PNPGSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL217117 | 0.82 | HINT1 (0.80) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL2675390 | 0.81 | HINT1 (0.71) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL9295418 | 0.81 | HINT1 (0.75) | PNPGSK3ARPS6KA3MAPK14HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140242600-A1 | IMAGING THE HETEROGENEOUS UPTAKE OF RADIOLABELED MOLECULES IN SINGLE LIVING CELLS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |