Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 1.00 |
| ▸ | PNP | P00491 | 1/20 | 0.71 |
| ▸ | GSK3A | P49840 | 2/20 | 0.70 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.70 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.62 |
| ▸ | ABL2 | P42684 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.59 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9605293 | 1.00 | ABCB1 (1.00) | ABCB1PNPGSK3ARPS6KA3MAPK14 | |
| SCHEMBL9607792 | 1.00 | ABCB1 (1.00) | ABCB1PNPGSK3ARPS6KA3MAPK14 | |
| SCHEMBL4629734 | 1.00 | ABCB1 (1.00) | ABCB1PNPGSK3ARPS6KA3MAPK14 | |
| Hydrochloric Acid SCHEMBL19666771 | 0.99 | ABCB1 (0.98) | ABCB1PNPGSK3ARPS6KA3MAPK14 | |
| SCHEMBL1271978 | 0.92 | ABCB1 (0.85) | ABCB1PNPGSK3ARPS6KA3MAPK14 | |
| SCHEMBL5738576 | 0.90 | ABCB1 (0.82) | ABCB1PNPGSK3ARPS6KA3MAPK14 | |
| SCHEMBL441535 | 0.87 | ABCB1 (0.77) | ABCB1GSK3ARPS6KA3MAPK14ADORA1 | |
| SCHEMBL11644877 | 0.87 | ABCB1 (0.77) | ABCB1GSK3ARPS6KA3MAPK14ADORA1 | |
| SCHEMBL14471384 | 0.87 | ABCB1 (0.77) | ABCB1GSK3ARPS6KA3MAPK14EGFR | |
| SCHEMBL1272109 | 0.87 | ABCB1 (0.77) | ABCB1PNPGSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160243149-A1 | NOVEL ANTI-VIRAL THERAPEUTIC | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-08-25 | — | — | US | claimed |
| US-20100143322-A1 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD., C/O THE B-NET (GB) | 2010-06-10 | — | — | US | claimed |
| US-7323319-B2 | RNA containing coenzymes, biotin, or fluorophores, and methods for their preparation and use | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2008-01-29 | — | — | US | claimed |
| US-20070009427-A1 | Compounds and methods for enhanced delivery to disease targets | GENERAL ELECTRIC COMPANY | 2007-01-11 | — | — | US | claimed |
| US-20070009428-A1 | Compounds and methods for enhanced delivery to disease targets | GENERAL ELECTRIC COMPANY | 2007-01-11 | — | — | US | claimed |
| EP-1604021-A4 | METHODS FOR IDENTIFYING ENZYME INHIBITORS AND PROTEIN KINASES | SMITHKLINE BEECHAM CORP (US) | 2006-11-08 | — | — | EP | claimed |
| US-20060234327-A1 | Methods for identifying enzyme inhibitors and protein kinases | BRAMSON HAROLD N | 2006-10-19 | — | — | US | claimed |
| EP-1604021-A2 | METHODS FOR IDENTIFYING ENZYME INHIBITORS AND PROTEIN KINASES | SMITHKLINE BEECHAM CORPORATION (US) | 2005-12-14 | — | — | EP | claimed |
| US-20040241649-A1 | RNA CONTAINING COENZYMES, BIOTIN, OR FLUOROPHORES, AND METHODS FOR THEIR PREPARATION AND USE | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2004-12-02 | — | — | US | claimed |
| WO-2004083175-A2 | METHODS FOR IDENTIFYING ENZYME INHIBITORS AND PROTEIN KINASES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-30 | — | — | WO | claimed |
| EP-1385998-A1 | BIOMOLECULE CHARACTERIZATION USING MASS SPECTROMETRY AND AFFINITY TAGS | Ciphergen Biosystems, Inc. (US) | 2004-02-04 | — | — | EP | claimed |
| EP-1352627-A2 | Reduction of hair growth | THE GILLETTE COMPANY (US) | 2003-10-15 | — | — | EP | claimed |
| US-20030077616-A1 | Biomolecule characterization using mass spectrometry and affinity tags | CIPHERGEN BIOSYSTEMS, INC. (US) | 2003-04-24 | — | — | US | claimed |
| WO-2002086168-A1 | BIOMOLECULE CHARACTERIZATION USING MASS SPECTROMETRY AND AFFINITY TAGS | CIPHERGEN BIOSYSTEMS, INC. (US) | 2002-10-31 | — | — | WO | claimed |
| US-5798241-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS | UNIVERSITE DE SHERBROOKE (CA) | 1998-08-25 | — | — | US | claimed |
| EP-0690924-A1 | ANTI-MICROBIAL AGENTS AND SCREENING METHOD THEREFOR | THE UNIVERSITY OF DUNDEE, UNIVERSITY COURT (GB) | 1996-01-10 | — | — | EP | claimed |
| WO-1994023059-A2 | ANTI-MICROBIAL AGENTS AND SCREENING METHOD THEREFOR | THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 1994-10-13 | — | — | WO | claimed |
| US-11197854-B1 | Inhibitors for targeting flaviviruses | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2021-12-14 | — | — | US | disclosed |
| EP-0439585-A1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. | EPIPHARM ALLERGIE SERVICE (AT) | 1991-08-07 | — | — | EP | disclosed |
| WO-1991002768-A1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS | EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11197854-B1 | Inhibitors for targeting flaviviruses | HAVCR2, MME, SPINT2 | ABCB1 2478/4885PNP 838/4885GSK3A 3361/4885 |
| US-20070009428-A1 | Compounds and methods for enhanced delivery to disease targets | SERPINA6, PAICS, FABP1 | ABCB1 572/4885PNP 1295/4885GSK3A 4605/4885 |
| US-20070009427-A1 | Compounds and methods for enhanced delivery to disease targets | SELPLG, FABP1, PIGO | ABCB1 599/4885PNP 2104/4885GSK3A 4550/4885 |
| US-20160243149-A1 | NOVEL ANTI-VIRAL THERAPEUTIC | RNASEH1, DNASE1L3, DNASE1 | ABCB1 4006/4885PNP 1008/4885GSK3A 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.