Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.75 |
| ▸ | GSK3A | P49840 | 3/20 | 0.69 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.69 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.69 |
| ▸ | HINT1 | P49773 | 9/20 | 0.65 |
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | KRAS | P01116 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954429 | 0.87 | GSK3A (0.69) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL15969638 | 0.86 | PNP (1.00) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL5219707 | 0.85 | GSK3A (0.80) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL6822440 | 0.84 | ABCB1 (0.73) | GSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL217117 | 0.81 | HINT1 (0.80) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL439016 | 0.80 | HINT1 (0.78) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL7915394 | 0.80 | HINT1 (0.71) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL784432 | 0.80 | HINT1 (0.75) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL9295418 | 0.80 | HINT1 (0.75) | PNPGSK3ARPS6KA3MAPK14HINT1 | |
| SCHEMBL9295421 | 0.80 | HINT1 (0.75) | PNPGSK3ARPS6KA3MAPK14HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385998-A1 | BIOMOLECULE CHARACTERIZATION USING MASS SPECTROMETRY AND AFFINITY TAGS | Ciphergen Biosystems, Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002086168-A1 | BIOMOLECULE CHARACTERIZATION USING MASS SPECTROMETRY AND AFFINITY TAGS | CIPHERGEN BIOSYSTEMS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |