Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4578255 | 0.95 | KDM4E (0.36) | KDM4EPKMHRH3CNR2FFAR3 | |
| SCHEMBL5276331 | 0.87 | FFAR3 (0.35) | KDM4EPKMFFAR3 | |
| SCHEMBL15254146 | 0.84 | HRH3 (0.34) | KDM4EPKMHRH3 | |
| SCHEMBL8853319 | 0.78 | L3MBTL1 (0.32) | — | |
| SCHEMBL25763081 | 0.77 | HRH3 (0.35) | KDM4EPKMHRH3CNR2 | |
| SCHEMBL18622068 | 0.75 | PKM (0.45) | KDM4EPKMHRH3CNR2 | |
| SCHEMBL5482221 | 0.73 | HRH3 (0.33) | KDM4EPKMHRH3CNR2 | |
| SCHEMBL4284742 | 0.73 | KDM4E (0.35) | KDM4EPKMCNR2 | |
| SCHEMBL21787533 | 0.73 | FFAR3 (0.35) | HRH3FFAR3 | |
| SCHEMBL4233436 | 0.73 | HRH3 (0.41) | KDM4EPKMHRH3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695162-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-02-02 | — | — | US | disclosed |
| WO-2014130513-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1996/4885PKM 2024/4885HRH3 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.