Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15974563 | 0.98 | ALOX5 (0.44) | ALOX5SLC6A2SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL29958333 | 0.79 | ALOX5 (0.44) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12066891 | 0.76 | ALOX5 (0.42) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13455948 | 0.75 | ALOX5 (0.44) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4950183 | 0.74 | — | — | |
| SCHEMBL29957322 | 0.73 | CTSK (0.46) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13455984 | 0.73 | ALOX5 (0.39) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL24017126 | 0.73 | CYP3A4 (0.43) | ALOX5SLC6A2SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL24017044 | 0.73 | CYP3A4 (0.43) | ALOX5SLC6A2SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL20571954 | 0.71 | KMT2A (0.42) | ALOX5CYP3A4CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958897-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2014130582-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2014-08-28 | — | — | WO | disclosed |