Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066891 | 0.87 | ALOX5 (0.42) | CTSKCTSSALOX5CHRNB2CHRNB4 | |
| SCHEMBL19348989 | 0.81 | CTSK (0.52) | CTSKCTSSATMMAPT | |
| SCHEMBL4715202 | 0.81 | CTSK (0.52) | CTSKCTSSATMMAPT | |
| SCHEMBL10896010 | 0.81 | CTSK (0.52) | CTSKCTSSATMMAPT | |
| SCHEMBL29958333 | 0.80 | ALOX5 (0.44) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13455984 | 0.80 | ALOX5 (0.39) | CTSKCTSSALOX5CHRNB2CHRNB4 | |
| SCHEMBL18216566 | 0.80 | CTSK (0.46) | CTSKCTSSATMPTPRBMAPT | |
| SCHEMBL13536928 | 0.80 | CTSK (0.46) | CTSKCTSSATMPTPRBMAPT | |
| SCHEMBL13920479 | 0.79 | MIF (0.48) | CTSKCTSSATMMAPTCA1 | |
| SCHEMBL3648561 | 0.78 | CTSS (0.49) | CTSKCTSSALOX5ATMPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |