Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958333 | 0.80 | ALOX5 (0.44) | ALOX5ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29957322 | 0.80 | CTSK (0.46) | ALOX5CTSKCTSSCHRNB2CHRNB4 | |
| SCHEMBL12066891 | 0.78 | ALOX5 (0.42) | ALOX5CTSKKMT2ACTSSALDH1A1 | |
| SCHEMBL13455948 | 0.77 | ALOX5 (0.44) | ALOX5OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL15974149 | 0.73 | ALOX5 (0.45) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL15974563 | 0.72 | ALOX5 (0.44) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10475340 | 0.70 | NQO2 (0.36) | ALOX5NPC1RAB9A | |
| SCHEMBL13762122 | 0.68 | NPC1 (0.56) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6621767 | 0.67 | — | — | |
| SCHEMBL29951738 | 0.67 | CTRB1 (0.49) | CTSSLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100061960-A1 | Amido Anti-Viral Compounds, Compositions, And Methods Of Use | SCHMITZ FRANZ ULRICH | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100061960-A1 | Amido Anti-Viral Compounds, Compositions, And Methods Of Use | HAVCR2, OAT, MAVS | ALOX5 636/4885TRPA1 2470/4885CTSK 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.