Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896010 | 0.85 | EPHX1 (0.54) | ALDH1A1EPHX1GAARAD52CYP1A2 | |
| Hydrochloric Acid SCHEMBL6340260 | 0.84 | SIGMAR1 (0.48) | ALDH1A1EPHX1GAARAD52SIGMAR1 | |
| SCHEMBL17525452 | 0.83 | KDM4E (0.54) | EPHX1GAARAD52CYP1A2TP53 | |
| SCHEMBL25477818 | 0.82 | RAD52 (0.55) | EPHX1GAARAD52CYP1A2SMN1; SMN2 | |
| SCHEMBL491722 | 0.82 | ALDH1A1 (0.80) | ALDH1A1RAD52SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL7776480 | 0.82 | EPHX1 (0.75) | ALDH1A1EPHX1SIGMAR1L3MBTL1KDM4E | |
| SCHEMBL25477820 | 0.80 | RAD52 (0.53) | EPHX1GAARAD52CYP1A2TP53 | |
| SCHEMBL491868 | 0.80 | EPHX1 (0.79) | ALDH1A1EPHX1GAACCR3KDM4E | |
| SCHEMBL15975480 | 0.80 | EPHX1 (0.79) | ALDH1A1EPHX1GAACCR3KDM4E | |
| SCHEMBL14004380 | 0.78 | ALDH1A1 (0.62) | ALDH1A1RAD52SIGMAR1FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1172359-A1 | N-SUBSTITUTED-N'-SUBSTITUTED UREA DERIVATIVE AND USE THEREOF AS TNF-$g(a) PRODUCTION INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-01-16 | — | — | EP | claimed |