SCHEMBL15975576

SCHEMBL15975576

CSCC(C)(C)C(=O)N(C)c1cn(-c2cccnc2)nc1Cl

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.35
ALDH1A1 P00352 4/20 0.33
DGAT1 O75907 1/20 0.33
GRM5 P41594 1/20 0.33
GRM1 Q13255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
MAPK1 P28482 1/20 0.32
MAT2A P31153 1/20 0.32
FAAH O00519 1/20 0.32
KCNH2 Q12809 1/20 0.32
HTT P42858 2/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
GPR119 Q8TDV5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18627130 0.90 RIPK1 (0.32) RIPK1ALDH1A1DGAT1GRM5GRM1
SCHEMBL4967866 0.90 RIPK1 (0.37) RIPK1ALDH1A1DGAT1GRM5GRM1
SCHEMBL18884253 0.89 DGAT1 (0.33) RIPK1ALDH1A1DGAT1GRM5GRM1
SCHEMBL16404269 0.86 GRM5 (0.36) RIPK1ALDH1A1DGAT1GRM5GRM1
SCHEMBL15346604 0.83 DGAT1 (0.35) ALDH1A1DGAT1GRM5GRM1NPC1
SCHEMBL2691588 0.83 ALDH1A1 (0.39) ALDH1A1DGAT1NPC1RAB9AMAPK1
SCHEMBL15346983 0.82 DGAT1 (0.37) DGAT1GRM5GRM1NPC1RAB9A
SCHEMBL15356826 0.82 ALDH1A1 (0.35) RIPK1ALDH1A1DGAT1GRM5GRM1
SCHEMBL4967836 0.81 FAAH (0.36) ALDH1A1DGAT1NPC1RAB9AMAPK1
SCHEMBL18627141 0.81 ALDH1A1 (0.33) RIPK1ALDH1A1DGAT1GRM5GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815271-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-08-26 US disclosed
US-8815271-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-08-26 US disclosed