Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.46 |
| ▸ | MDM4 | O15151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348266 | 0.90 | TNF (0.46) | TNFMDM4TP53CASP3TLR2 | |
| SCHEMBL16774592 | 0.83 | TNF (0.45) | TNFMDM4TP53CASP3 | |
| SCHEMBL6044028 | 0.83 | LMNA (0.50) | TNFMDM4TP53CASP3MDM2 | |
| SCHEMBL17742420 | 0.80 | CD209 (0.49) | TNFMDM4TP53CASP3TLR2 | |
| SCHEMBL13163903 | 0.80 | PRKCA (0.47) | TNF | |
| SCHEMBL13163947 | 0.79 | PYGB (0.44) | TNFMDM4TP53CASP3 | |
| SCHEMBL13184036 | 0.79 | PYGB (0.44) | TNFMDM4TP53CASP3 | |
| SCHEMBL30781815 | 0.79 | CASP3 (0.54) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL14402257 | 0.78 | LMNA (0.42) | TNFCASP3 | |
| SCHEMBL13904007 | 0.77 | PRKCA (0.45) | TNFMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816050-B2 | Method of preparing glycopeptides | THE SCRIPPS RESEARCH INSTITUTE | 2014-08-26 | — | — | US | disclosed |