SCHEMBL15977620

SCHEMBL15977620

c1ccc(-c2ccc(-c3ccc4c(-c5cc6ccccc6c6ccccc56)c5ccccc5c(-c5cccc6ccccc56)c4c3)cc2)nc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.42
HPGD P15428 4/20 0.42
KDM4E B2RXH2 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 3/20 0.42
NPC1 O15118 2/20 0.42
MAPT P10636 2/20 0.42
TP53 P04637 2/20 0.42
DHODH Q02127 2/20 0.41
HTR2C P28335 2/20 0.40
TGFBR1 P36897 1/20 0.40
DCTPP1 Q9H773 1/20 0.37
CYP11B1 P15538 1/20 0.36
LMNA P02545 4/20 0.35
ENPP3 O14638 1/20 0.35
ENPP1 P22413 1/20 0.35
RAB9A P51151 1/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24812248 0.94 DHODH (0.45) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL15977598 0.90 HPGD (0.40) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL15977510 0.90 KDM4E (0.40) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL276038 0.87 MAPK1 (0.46) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL24353135 0.86 MAPK1 (0.45) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL15977863 0.85 PIK3CA (0.39) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL15977504 0.85 CYP11B1 (0.39) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL15977841 0.85 ALDH1A1 (0.44) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL15977677 0.84 ADORA3 (0.39) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1
SCHEMBL10030061 0.83 MAPK1 (0.47) MAPK1HPGDKDM4ESMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 MAPK1 742/4885HPGD 4077/4885KDM4E 3416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.