Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401003 | 0.84 | ELANE (0.49) | TRPA1MAPTLMNATP53MEN1 | |
| SCHEMBL6593684 | 0.84 | CYP1A2 (0.50) | TRPA1MAPTLMNATP53NQO2 | |
| SCHEMBL30351269 | 0.81 | DHODH (0.43) | TRPA1MAPTLMNATP53MEN1 | |
| SCHEMBL29029739 | 0.77 | ADRB2 (0.45) | MAPTLMNAGAAHPGDCYP1A2 | |
| SCHEMBL2905327 | 0.77 | GRM2 (0.49) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL24777192 | 0.76 | MPO (0.41) | MEN1KMT2AALOX15HPGDCYP1A2 | |
| SCHEMBL20793006 | 0.76 | NQO2 (0.41) | TRPA1MAPTLMNANQO2CYP1A2 | |
| SCHEMBL4173614 | 0.76 | CYP1A2 (0.50) | TRPA1MAPTLMNAKMT2ACYP1A2 | |
| SCHEMBL8127677 | 0.76 | POLB (0.47) | MAPTMEN1GAAKMT2AALOX15 | |
| SCHEMBL29892219 | 0.76 | CYP1A2 (0.41) | TRPA1MAPTLMNANQO2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873694-B2 | Imidazole quinoline-based immune system modulators | JANUS BIOTHERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20140242121-A1 | NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140242121-A1 | NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS | IRF3, HLA-DRB1, IFNG | TRPA1 973/4885MAPT 12/4885LMNA 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.