SCHEMBL15978669

SCHEMBL15978669

CCCCC1C(=O)N(CCS(=O)(=O)O)C(=O)N(CCS(=O)(=O)O)C1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
CYP3A4 P08684 2/20 0.38
HPGD P15428 2/20 0.38
TP53 P04637 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS1 P23219 1/20 0.38
RAB9A P51151 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33
ELANE P08246 1/20 0.33
GAA P10253 2/20 0.32
CDC25A P30304 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15978128 0.96 ALDH1A1 (0.35) ALDH1A1MAPTCYP3A4HPGDTP53
SCHEMBL18257382 0.91 ALDH1A1 (0.33) ALDH1A1MAPTCYP3A4HPGDTP53
SCHEMBL31681885 0.81 SMN1; SMN2 (0.43) ALDH1A1MAPTCYP3A4HPGDTP53
SCHEMBL7674510 0.78 PDE4A (0.42) ALDH1A1MAPTCYP3A4HPGDTP53
SCHEMBL1426468 0.76 ELANE (0.48) ALDH1A1MAPTCYP3A4HPGDTP53
SCHEMBL10444309 0.73 KDM4E (0.42) ALDH1A1MAPTTP53PTGS1KDM4E
SCHEMBL15978134 0.73 ALDH1A1 (0.36) ALDH1A1MAPTCYP3A4HPGDTP53
SCHEMBL1263039 0.70 L3MBTL1 (0.50) ALDH1A1MAPTCYP3A4HPGDTP53
SCHEMBL21694442 0.69 ALDH1A1 (0.45) ALDH1A1MAPTCYP3A4HPGDTP53
SCHEMBL12578303 0.69 PTGS1 (0.31) LMNACYP2C19PTGS1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170322358-A1 POLARIZING PLATE, FRONT PANEL OF DISPLAY DEVICE, DISPLAY APPARATUS, SUBSTRATE OF TOUCH PANEL, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-20150253479-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed
US-20140242300-A1 POLARIZER, POLARIZING PLATE USING THE SAME, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 ALDH1A1 4014/4885MAPT 4098/4885CYP3A4 4760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.