Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681885 | 0.96 | SMN1; SMN2 (0.43) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL25867958 | 0.84 | F2 (0.39) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL1426468 | 0.82 | ELANE (0.48) | SMN1; SMN2TP53GAAPTGS1ALDH1A1 | |
| SCHEMBL15978669 | 0.78 | ALDH1A1 (0.38) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL1263039 | 0.76 | L3MBTL1 (0.50) | TP53GAAPTGS1ALDH1A1CYP3A4 | |
| SCHEMBL15978134 | 0.76 | ALDH1A1 (0.36) | TP53GAAPTGS1ALDH1A1CYP3A4 | |
| SCHEMBL21694442 | 0.76 | ALDH1A1 (0.45) | SMN1; SMN2TP53GAAPTGS1ALDH1A1 | |
| SCHEMBL15978128 | 0.75 | ALDH1A1 (0.35) | TP53PTGS1ALDH1A1CYP3A4MAPT | |
| SCHEMBL7680940 | 0.75 | SMN1; SMN2 (0.44) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL11082084 | 0.73 | TP53 (0.40) | SMN1; SMN2TP53PTGS1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365068-B1 | IN SOLVENT | HYDRO-QUEBEC (CA) | 2002-04-02 | — | — | US | disclosed |
| US-6171522-B1 | Heterocyclic aromatic anion salts, and their uses as ionic conducting materials | Hydro-Qu{acute over (e)}bec (CA) | 2001-01-09 | — | — | US | disclosed |