Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.60 |
| ▸ | WNT3A | P56704 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12440170 | 0.91 | PDE4B (0.60) | CTNNB1WNT3AALDH1A1CYP1A2HPGD | |
| SCHEMBL15979735 | 0.89 | CTNNB1 (0.62) | CTNNB1WNT3ATAS1R3TAS1R1PAX8 | |
| SCHEMBL11469659 | 0.87 | CTNNB1 (0.60) | CTNNB1WNT3AALDH1A1CYP1A2HPGD | |
| SCHEMBL1527427 | 0.87 | CTNNB1 (0.73) | CTNNB1WNT3AALDH1A1CYP1A2HPGD | |
| SCHEMBL29923058 | 0.87 | CTNNB1 (0.73) | CTNNB1WNT3AALDH1A1CYP1A2HPGD | |
| SCHEMBL6339402 | 0.85 | CTNNB1 (0.58) | CTNNB1WNT3ATAS1R3TAS1R1PDE4B | |
| SCHEMBL8214127 | 0.84 | TAS1R3 (0.55) | CTNNB1WNT3AALDH1A1CYP1A2HPGD | |
| SCHEMBL5188941 | 0.84 | ALDH1A1 (0.59) | CTNNB1WNT3AALDH1A1CYP1A2HPGD | |
| SCHEMBL6085421 | 0.83 | CTNNB1 (0.56) | CTNNB1WNT3AALDH1A1KMT2ATAS1R3 | |
| SCHEMBL31525615 | 0.83 | ALDH1A1 (0.63) | CTNNB1WNT3AALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1783221-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX Corp. (US) | 2007-05-09 | — | — | EP | disclosed |
| US-7026487-B2 | Amines substituted with a dihydronaphthalenyl, chromenyl, or thiochromenyl group, a pyridyl group and an alkyl group, having retinoid-like biological activity | ALLERGAN, INC. (US) | 2006-04-11 | — | — | US | disclosed |
| US-7001729-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2006-02-21 | — | — | US | disclosed |
| US-6906175-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor. | MIGENIX CORP. (US) | 2005-06-14 | — | — | US | disclosed |
| US-6906174-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-06-14 | — | — | US | disclosed |
| US-6902908-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-06-07 | — | — | US | disclosed |
| US-6887670-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050064530-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-03-24 | — | — | US | disclosed |
| US-20050019835-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-01-27 | — | — | US | disclosed |
| US-20050003352-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-01-06 | — | — | US | disclosed |
| EP-0485587-A1 | INGESTIBLES CONTAINING SUBSTANTIALLY TASTELESS SWEETNESS INHIBITORS AS BITTER TASTE REDUCERS OR SUBSTANTIALLY TASTELESS BITTER INHIBITORS AS SWEET TASTE REDUCERS. | BIORESEARCH INC (US) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991018523-A1 | INGESTIBLES CONTAINING SUBSTANTIALLY TASTELESS SWEETNESS INHIBITORS AS BITTER TASTE REDUCERS OR SUBSTANTIALLY TASTELESS BITTER INHIBITORS AS SWEET TASTE REDUCERS | BIORESEARCH, INC. (US) | 1991-12-12 | — | — | WO | disclosed |
| EP-0156317-A2 | Foodstuffs containing sweetness inhibiting agents and process for inhibiting the sweetness perception of a foodstuff | GENERAL FOODS CORPORATION (US) | 1985-10-02 | — | — | EP | disclosed |
| US-4544565-A | ARYLALKYLKETONES | GENERAL FOODS CORPORATION (US) | 1985-10-01 | — | — | US | disclosed |
| US-4207241-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS AND ANTIPRURITIC AGENTS | SYNTEX CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4097674-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTIPRURITIC AGENTS, ANALGESICS | SYNTEX CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4051233-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-4001301-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTI-PRURITIC | SYNTEX CORPORATION (PM) | 1977-01-04 | — | — | US | disclosed |
| US-3998966-A | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof | SYNTEX CORPORATION (PM) | 1976-12-21 | — | — | US | disclosed |
| US-3978124-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050003352-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | GART, TMEM165, SLC43A3 | CTNNB1 3084/4885WNT3A 1452/4885ALDH1A1 2810/4885 |
| US-20050064530-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | GART, TMEM165, SLC43A3 | CTNNB1 3084/4885WNT3A 1452/4885ALDH1A1 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.