Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038141 | 0.92 | LTA4H (0.46) | LTA4HTSHRALDH1A1CYP3A4MAPK1 | |
| Trifluoroacetic Acid SCHEMBL10588931 | 0.85 | TSHR (0.41) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| Benzene SCHEMBL28132981 | 0.69 | LTA4H (0.87) | LTA4HCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1331014 | 0.69 | LTA4H (0.87) | LTA4HCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL36192 | 0.69 | LTA4H (0.87) | LTA4HCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL28386097 | 0.67 | LTA4H (0.83) | LTA4HCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| Water SCHEMBL27940226 | 0.67 | LTA4H (0.83) | LTA4HCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5487251 | 0.67 | LTA4H (0.38) | LTA4HTSHRTDP1TP53 | |
| SCHEMBL22319104 | 0.67 | LTA4H (0.83) | LTA4HCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| Biphenyl SCHEMBL15361769 | 0.67 | LTA4H (0.52) | LTA4HCYP1A2CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232285-A1 | Sulfonyl-1,2,4-triazole salts | UNIVERSITE DE MONTREAL (CA) | 2012-09-13 | — | — | US | disclosed |
| US-20110178306-A1 | Sulphonyl-1,2,4-Triazole Salts | PHOSTECH LITHIUM INC. (CA) | 2011-07-21 | — | — | US | disclosed |
| US-7919629-B2 | Sulphonyl-1,2,4-triazole salts | PHOSTECH LITHIUM INC. (CA) | 2011-04-05 | — | — | US | disclosed |
| US-20090292105-A1 | SULPHONYL-1,2,4-TRIAZOLE SALTS | PHOSTECH LITHIUM INC. (CA) | 2009-11-26 | — | — | US | disclosed |
| WO-2007068822-A2 | SULPHONYL-1,2,4-TRIAZOLE SALTS | PHOSTECH LITHIUM INC. (CA) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178306-A1 | Sulphonyl-1,2,4-Triazole Salts | TST, STS, SQOR | LTA4H 4083/4885CYP1A2 432/4885CYP2C9 118/4885 |
| US-20090292105-A1 | SULPHONYL-1,2,4-TRIAZOLE SALTS | TST, STS, SQOR | LTA4H 4083/4885CYP1A2 432/4885CYP2C9 118/4885 |
| US-20120232285-A1 | Sulfonyl-1,2,4-triazole salts | STS, TST, FIS1 | LTA4H 4562/4885CYP1A2 740/4885CYP2C9 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.