⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267337 | 0.82 | — | — | |
| SCHEMBL17240321 | 0.77 | — | — | |
| SCHEMBL2774703 | 0.76 | — | — | |
| SCHEMBL11863697 | 0.75 | — | — | |
| SCHEMBL8893283 | 0.71 | — | — | |
| SCHEMBL779460 | 0.71 | — | — | |
| SCHEMBL677501 | 0.70 | — | — | |
| SCHEMBL779461 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL1761289 | 0.68 | CYP3A4 (0.37) | — | |
| SCHEMBL17240322 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252620-B1 | SILAHYDROCARBYL ESTERS OF 3-CHLORO-2-TRIFLUOROMETHYLPROPIONIC ACID, THEIR PREPARATION AND PREPARATION OF THE CORRESPONDING ACRYLIC ACID ESTERS | DOW CORNING TORAY CO LTD (JP) | 2013-04-10 | — | — | EP | claimed |
| US-7919642-B2 | Silahydrocarbyl esters of 3-chloro-2-trifluoromethylpropionic acid, their preparation and preparation of the corresponding acrylic acid esters | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-04-05 | — | — | US | claimed |
| US-20100311999-A1 | Silahydrocarbyl Esters Of 3-Chloro-2-Trifluoromethylpropionic Acid, Their Preparation and Preparation Of The Corresponding Acrylic Acid Esters | DOW TORAY CO., LTD. (JP) | 2010-12-09 | — | — | US | claimed |
| EP-2252620-A1 | SILAHYDROCARBYL ESTERS OF 3-CHLORO-2-TRIFLUOROMETHYLPROPIONIC ACID, THEIR PREPARATION AND PREPARATION OF THE CORRESPONDING ACRYLIC ACID ESTERS | Dow Corning Toray Co., Ltd. (JP) | 2010-11-24 | — | — | EP | claimed |
| WO-2009082027-A1 | SILAHYDROCARBYL ESTERS OF 3-CHLORO-2-TRIFLUOROMETHYLPROPIONIC ACID, THEIR PREPARATION AND PREPARATION OF THE CORRESPONDING ACRYLIC ACID ESTERS | DOW CORNING TORAY CO., LTD. (JP) | 2009-07-02 | — | — | WO | claimed |
| EP-2252620-B1 | SILAHYDROCARBYL ESTERS OF 3-CHLORO-2-TRIFLUOROMETHYLPROPIONIC ACID, THEIR PREPARATION AND PREPARATION OF THE CORRESPONDING ACRYLIC ACID ESTERS | DOW CORNING TORAY CO LTD (JP) | 2013-04-10 | — | — | EP | disclosed |
| CN-101918414-B | Silahydrocarbyl esters of 3-chloro-2-trifluoromethylpropionic acid, their preparation and preparation of the corresponding acrylic acid esters | DOW CORNING TORAY CO LTD | 2013-01-02 | — | — | CN | disclosed |
| US-7919642-B2 | Silahydrocarbyl esters of 3-chloro-2-trifluoromethylpropionic acid, their preparation and preparation of the corresponding acrylic acid esters | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7919642-B2 | Silahydrocarbyl esters of 3-chloro-2-trifluoromethylpropionic acid, their preparation and preparation of the corresponding acrylic acid esters | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| CN-101918414-A | Silahydrocarbyl esters of 3-chloro-2-trifluoromethylpropionic acid, their preparation and preparation of the corresponding acrylic acid esters | DOW CORNING TORAY CO LTD | 2010-12-15 | — | — | CN | disclosed |
| US-20100311999-A1 | Silahydrocarbyl Esters Of 3-Chloro-2-Trifluoromethylpropionic Acid, Their Preparation and Preparation Of The Corresponding Acrylic Acid Esters | DOW TORAY CO., LTD. (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100311999-A1 | Silahydrocarbyl Esters Of 3-Chloro-2-Trifluoromethylpropionic Acid, Their Preparation and Preparation Of The Corresponding Acrylic Acid Esters | DOW TORAY CO., LTD. (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2252620-A1 | SILAHYDROCARBYL ESTERS OF 3-CHLORO-2-TRIFLUOROMETHYLPROPIONIC ACID, THEIR PREPARATION AND PREPARATION OF THE CORRESPONDING ACRYLIC ACID ESTERS | Dow Corning Toray Co., Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| EP-2252620-A1 | SILAHYDROCARBYL ESTERS OF 3-CHLORO-2-TRIFLUOROMETHYLPROPIONIC ACID, THEIR PREPARATION AND PREPARATION OF THE CORRESPONDING ACRYLIC ACID ESTERS | Dow Corning Toray Co., Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| JP-2009173637-A | ORGANOSILICON COMPOUND AND PRODUCTION METHOD THEREOF | DOW CORNING TORAY CO LTD | 2009-08-06 | — | — | JP | disclosed |
| WO-2009082027-A1 | SILAHYDROCARBYL ESTERS OF 3-CHLORO-2-TRIFLUOROMETHYLPROPIONIC ACID, THEIR PREPARATION AND PREPARATION OF THE CORRESPONDING ACRYLIC ACID ESTERS | DOW CORNING TORAY CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009082027-A1 | SILAHYDROCARBYL ESTERS OF 3-CHLORO-2-TRIFLUOROMETHYLPROPIONIC ACID, THEIR PREPARATION AND PREPARATION OF THE CORRESPONDING ACRYLIC ACID ESTERS | DOW CORNING TORAY CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |