Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 16/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004094 | 0.94 | GPR142 (0.64) | GPR142FAAH | |
| SCHEMBL16004157 | 0.91 | GPR142 (0.58) | GPR142FAAH | |
| SCHEMBL16003998 | 0.91 | GPR142 (0.51) | GPR142ALDH1A1RAB9AFAAH | |
| SCHEMBL16004310 | 0.89 | GPR142 (0.53) | GPR142MAPTRAB9A | |
| SCHEMBL16004311 | 0.84 | GPR142 (0.64) | GPR142ALDH1A1RAB9A | |
| SCHEMBL16004106 | 0.82 | GPR142 (0.51) | GPR142ALDH1A1MAPTRAB9AFAAH | |
| SCHEMBL16004316 | 0.81 | GPR142 (0.52) | GPR142MAPTRAB9AFAAH | |
| SCHEMBL16004158 | 0.81 | RAB9A (0.48) | GPR142ALDH1A1MAPTRAB9A | |
| SCHEMBL16004092 | 0.80 | GPR142 (0.53) | GPR142 | |
| SCHEMBL16004105 | 0.80 | GPR142 (0.55) | GPR142FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133414-A2 | HETEROCYCLIC TGR5 BILE ACID RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ ЛЛС (US) | 2014-09-04 | — | — | WO | disclosed |