SCHEMBL16005483

SCHEMBL16005483

c1ccc2cc(-c3ncco3)ccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.50
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 3/20 0.50
KDM4E B2RXH2 2/20 0.50
TP53 P04637 2/20 0.50
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
PKM P14618 1/20 0.50
KLF5 Q13887 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HPGDS O60760 1/20 0.50
CYP1A2 P05177 4/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
NOTUM Q6P988 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26260185 0.92 LTA4H (0.55) LTA4HSMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL26260205 0.90 LTA4H (0.49) LTA4HSMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL16159285 0.87 LTA4H (0.51) LTA4HSMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL16159831 0.85 LTA4H (0.56) LTA4HSMN1; SMN2ALDH1A1HSD17B10TSHR
SCHEMBL16159667 0.82 LTA4H (0.48) LTA4HSMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL17704302 0.82 LTA4H (0.42) LTA4HSMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL17704369 0.81 SMN1; SMN2 (0.42) LTA4HSMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL22223105 0.79 LTA4H (0.42) LTA4HSMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL16159845 0.78 LTA4H (0.54) LTA4HHPGDSCCNCCDK8ESR1
SCHEMBL16159167 0.78 HPGDS (0.42) LTA4HSMN1; SMN2ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111983743-B Optical filter, image pickup device, and camera module JSR株式会社 2024-02-27 CN disclosed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
CN-111801606-B Optical filter, camera module, and electronic apparatus JSR株式会社 2022-06-07 CN disclosed
CN-110678785-B Optical filter for ambient light sensor, and electronic device JSR株式会社 2022-04-05 CN disclosed
CN-108345059-B Optical filter and use thereof JSR株式会社 2021-08-03 CN disclosed
CN-111983743-A Optical filter, imaging device, and camera module JSR株式会社 2020-11-24 CN disclosed
CN-111801606-A Optical filter, camera module, and electronic apparatus JSR株式会社 2020-10-20 CN disclosed
EP-3660934-A1 ORGANIC LIGHT EMITTING ELEMENT CAPABLE OF DRIVING AT LOW VOLTAGE AND HAVING HIGH EFFICIENCY AND LONG LIFE CHARACTERISTICS SFC Co., Ltd. (KR) 2020-06-03 EP disclosed
CN-110678785-A Optical filter for ambient light sensor JSR株式会社 2020-01-10 CN disclosed
US-20180072753-A1 NOVEL ORGANIC HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD. (KR) 2018-03-15 US disclosed
EP-2774923-B1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE UNIV NAGOYA NAT UNIV CORP (JP) 2016-05-18 EP disclosed
US-8993777-B2 Method for producing phenyl-substituted heterocyclic derivative NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2015-03-31 US disclosed
US-8993777-B2 Method for producing phenyl-substituted heterocyclic derivative NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2015-03-31 US disclosed
US-8993777-B2 Method for producing phenyl-substituted heterocyclic derivative NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2015-03-31 US disclosed
US-20140275549-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-09-18 US disclosed
US-20140275549-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-09-18 US disclosed
US-20140275549-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-09-18 US disclosed
EP-2774923-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE National University Corporation Nagoya University (JP) 2014-09-10 EP disclosed
CN-1071834-A The compositions and the method for treatment cancer FUJI PHOTO FILM CO LTD (JP) 1993-05-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180072753-A1 NOVEL ORGANIC HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE COMPRISING SAME OR10J3, CRY1, NR2E3 LTA4H 494/4885SMN1; SMN2 4221/4885ALDH1A1 133/4885
US-20140275549-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE PAH, DDT, NISCH LTA4H 1660/4885SMN1; SMN2 4568/4885ALDH1A1 1162/4885
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND NUDC, CCNL2, SPIN3 LTA4H 1665/4885SMN1; SMN2 1455/4885ALDH1A1 2125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.