⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225607 | 0.72 | — | — | |
| Magnesium Chloride Anhydrous SCHEMBL28548324 | 0.72 | NCF1 (0.39) | — | |
| SCHEMBL10902530 | 0.72 | HRH3 (0.35) | — | |
| SCHEMBL4960 | 0.71 | — | — | |
| SCHEMBL10904415 | 0.71 | GNAO1 (0.47) | — | |
| SCHEMBL364269 | 0.67 | — | — | |
| SCHEMBL2735017 | 0.65 | GNAI3 (0.50) | — | |
| Hydrochloric Acid SCHEMBL490234 | 0.65 | — | — | |
| SCHEMBL6946157 | 0.65 | — | — | |
| SCHEMBL13775366 | 0.63 | NCF1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3170479-A | — | — | None | — | — | JP | disclosed |
| EP-4096662-A1 | PROCESS FOR PREPARATION OF LASMIDITAN | Glenmark Life Sciences Limited (IN) | 2022-12-07 | — | — | EP | disclosed |
| EP-2118110-B1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-07-25 | — | — | EP | disclosed |
| EP-2398796-A1 | HETEROCYCLIC DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | Merck Canada Inc. (CA) | 2011-12-28 | — | — | EP | disclosed |
| US-20110301143-A1 | HETEROCYCLIC DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK CANADA INC. (CA) | 2011-12-08 | — | — | US | disclosed |
| US-7919506-B2 | Dibenzyl amine compounds and derivatives | PFIZER INC. (US) | 2011-04-05 | — | — | US | disclosed |
| WO-2010094126-A1 | HETEROCYCLIC DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-08-26 | — | — | WO | disclosed |
| EP-2118110-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | Bristol-Myers Squibb Company (US) | 2009-11-18 | — | — | EP | disclosed |
| US-7538102-B2 | Compounds for the treatment of Hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-05-26 | — | — | US | disclosed |
| CN-101437804-A | Dibenzyl amine compounds and derivatives | PFIZER PROD INC (US) | 2009-05-20 | — | — | CN | disclosed |
| US-4160031-A | Antihistaminic and appetite stimulating 10,11-dihydro-3-carboxycyproheptadine | MERCK & CO., INC. (US) | 1979-07-03 | — | — | US | disclosed |
| US-4148903-A | Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines | MERCK & CO., INC. (US) | 1979-04-10 | — | — | US | disclosed |
| EP-0000716-A2 | Pyrrolo(2,1-b)(3)benzazepine derivatives, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1979-02-21 | — | — | EP | disclosed |
| US-4104398-A | 3-Lower alkoxycyproheptadines as serotonin inhibitors | MERCK & CO., INC. (US) | 1978-08-01 | — | — | US | disclosed |
| US-4031222-A | ANTIEXTRAPYRAMIDAL, ANTIPSYCHOTIC, ENANTIOMERS, TRANQUILIZERS, ANTICHOLINERGIC | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4031223-A | ANTIEXTRAPYRAMIDAL, ANTIPSYCHOTIC, ENANTIOMERS, TRANQUILIZERS, ANTICHOLINERGIC | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4022902-A | APPETITE STIMULANTS AND ANTIHISTAMINES | MERCK & CO., INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-4021561-A | ANTIPSYCHOTICS | MERCK & CO., INC. (US) | 1977-05-03 | — | — | US | disclosed |
| US-4020169-A | FROM ARYL IODIDE OR BROMIDE AND TRIFLUOROMETHYL THIO COPPER | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |
| US-3981877-A | APPETITE STIMULANTS | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |