Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208417 | 0.88 | TLR8 (0.47) | TLR8STAT3GPR119SMN1; SMN2USP2 | |
| SCHEMBL14678562 | 0.77 | SMN1; SMN2 (0.40) | STAT3SMN1; SMN2ARMAPTTSHR | |
| SCHEMBL14678033 | 0.76 | AR (0.40) | SMN1; SMN2ARLMNA | |
| SCHEMBL16009227 | 0.76 | BRD4 (0.40) | STAT3SMN1; SMN2ARMAPTTSHR | |
| SCHEMBL20873847 | 0.75 | USP2 (0.53) | TLR8SMN1; SMN2USP2ACKR3CHRM2 | |
| SCHEMBL8242595 | 0.75 | USP2 (0.61) | TLR8SMN1; SMN2USP2ACKR3CHRM2 | |
| SCHEMBL38654186 | 0.72 | GPR119 (0.54) | GPR119SMN1; SMN2USP2MAPTHTT | |
| SCHEMBL15353080 | 0.71 | SMN1; SMN2 (0.72) | SMN1; SMN2USP2ACKR3CHRM2CHRM4 | |
| SCHEMBL17782085 | 0.71 | HPGD (0.49) | TLR8SMN1; SMN2USP2ACKR3CHRM2 | |
| SCHEMBL4832556 | 0.71 | GPR119 (0.57) | GPR119ACKR3CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256740-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256740-A1 | COMPOUNDS AND METHODS | RORC, RORB, RORA | TLR8 556/4885STAT3 253/4885GPR119 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.