Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 2/20 | 0.34 |
| ▸ | ATP4B | P51164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087582 | 0.76 | HSD17B1 (0.42) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29291122 | 0.74 | RAB9A (0.37) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28014367 | 0.73 | HPGD (0.39) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21074260 | 0.68 | AR (0.41) | HPGDSMN1; SMN2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL18696938 | 0.68 | HPGD (0.62) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3626478 | 0.67 | RAB9A (0.61) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3282094 | 0.67 | CA12 (0.50) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL726662 | 0.67 | ALDH1A1 (0.39) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7590488 | 0.66 | HPGD (0.60) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL22675054 | 0.66 | HPGD (0.39) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2992058-A1 | TINTING ENHANCERS FOR HARD COAT TINTING | Essilor International (Compagnie Générale D'Optique) (FR) | 2016-03-09 | — | — | EP | disclosed |
| EP-2964828-A2 | ARYLENE CARRIERS FOR ENHANCED POLYCARBONATE TINTING | Essilor International (Compagnie Générale D'Optique) (FR) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014177580-A1 | TINTING ENHANCERS FOR HARD COAT TINTING | Essilor International (Compagnie Générale d'Optique) (FR) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014135656-A2 | ARYLENE CARRIERS FOR ENHANCED POLYCARBONATE TINTING | Essilor International (Compagnie Générale d'Optique) (FR) | 2014-09-12 | — | — | WO | disclosed |