⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28465430 | 0.92 | ALDH1A1 (0.39) | — | |
| SCHEMBL7479452 | 0.85 | ACHE (0.41) | — | |
| SCHEMBL5778859 | 0.79 | CYP1A1 (0.55) | — | |
| SCHEMBL7839219 | 0.78 | CYP1A1 (0.55) | — | |
| SCHEMBL15066961 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL11099027 | 0.77 | ABL1 (0.52) | — | |
| SCHEMBL28824959 | 0.77 | ABL1 (0.52) | — | |
| SCHEMBL20240552 | 0.77 | HTT (0.55) | — | |
| SCHEMBL15905122 | 0.76 | MTNR1A (0.48) | — | |
| SCHEMBL77754 | 0.76 | CA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| US-20230365559-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | AUCKLAND UNISERVICES LIMITED (NZ) | 2023-11-16 | — | — | US | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| CN-116669725-A | Novel aminopyridine and use thereof in the treatment of cancer | 奥克兰联合服务有限公司 | 2023-08-29 | — | — | CN | claimed |
| EP-4217357-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | Auckland Uniservices Limited (NZ) | 2023-08-02 | — | — | EP | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| US-20230052586-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-02-16 | — | — | US | claimed |
| CN-114044742-B | Chiral primary amine malonamide compound and preparation method and application thereof | 河北工业大学 | 2023-02-10 | — | — | CN | claimed |
| EP-3898588-B1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-01-11 | — | — | EP | claimed |
| US-20220396579-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2022-12-15 | — | — | US | claimed |
| US-4906250-A | Process for the preparation of water-insoluble azo dyes on the fiber: impregnating with coupling component and treating with diazonium salt of 4-chloro-2,5-dialkoxy aniline | HOECHST AKTIENGESELLSCHAFT, A CORP. OF THE FEDERAL REPUBLIC OF GERMANY (DE) | 1990-03-06 | — | — | US | claimed |
| EP-0312003-A2 | Process of manufacturing water insolubles azodyes on the fibre | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-19 | — | — | EP | claimed |
| US-4769493-A | Process for producing tetrafluorophthalic acid | SDS BIOTECH K.K. (JP) | 1988-09-06 | — | — | US | claimed |
| EP-0259663-A1 | Process for producing tetrafluorophihalic acid | SDS Biotech K.K. (JP) | 1988-03-16 | — | — | EP | claimed |
| US-4696675-A | Process for preparing water-insoluble blue azo dyes on the fiber: hydroxynaphthoic amide and diazotized di-alkoxy-benzidine | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-29 | — | — | US | claimed |
| EP-0199973-A2 | Process for the production on the fibre of water insoluble azo dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-05 | — | — | EP | claimed |
| US-4440845-A | CHARGE TRANSFER COMPOUND | RICOH CO., LTD. (JP) | 1984-04-03 | — | — | US | claimed |
| US-4356193-A | Animal feed and process | THE UPJOHN COMPANY (US) | 1982-10-26 | — | — | US | claimed |
| US-4058516-A | DISAZO DYES | SANDOZ LTD. (CH) | 1977-11-15 | — | — | US | claimed |
| US-3950538-A | Anti-inflammatory methods utilizing certain thioureas | THE DOW CHEMICAL COMPANY (US) | 1976-04-13 | — | — | US | claimed |