Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16013937 | 0.81 | PNMT (0.35) | MEN1MAPTKMT2ALMNAKDM1A | |
| SCHEMBL16013892 | 0.80 | TSHR (0.43) | BACE1MAOBKDM1AHCAR3HCAR2 | |
| SCHEMBL16013588 | 0.80 | KDM1A (0.39) | KDM1AHCAR3HCAR2 | |
| SCHEMBL16196765 | 0.78 | HCAR3 (0.40) | MEN1MAPTKMT2ALMNAMAOB | |
| SCHEMBL16196766 | 0.78 | MAPT (0.37) | MAPTKDM1AHCAR3HCAR2 | |
| SCHEMBL16196764 | 0.77 | KDM1A (0.36) | KIF11KDM1AHCAR3HCAR2 | |
| SCHEMBL16013734 | 0.76 | TSHR (0.41) | BACE1MAOBKDM1A | |
| SCHEMBL30152324 | 0.75 | KIF11 (0.46) | BACE1KIF11MPOHSP90AA1CXCR5 | |
| SCHEMBL16196762 | 0.74 | KDM1A (0.38) | KDM1AHCAR3HCAR2 | |
| SCHEMBL16196877 | 0.73 | NR4A1 (0.44) | KIF11MEN1KMT2ALMNAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| EP-2964025-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014135095-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | DDT, DHODH, ACHE | BACE1 3345/4885KIF11 1528/4885MPO 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.