Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.35 |
| ▸ | GCK | P35557 | 4/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14658369 | 0.91 | GCK (0.34) | TRPA1GCKMALT1TRPV1KCNH2 | |
| SCHEMBL27925516 | 0.89 | GCK (0.35) | TRPA1GCKMALT1TRPV1KCNH2 | |
| SCHEMBL16014575 | 0.88 | ALDH1A1 (0.39) | MAPTTRPA1GCKMALT1KCNH2 | |
| SCHEMBL29185079 | 0.87 | TRPA1 (0.35) | TRPA1GCKMALT1TRPV1KCNH2 | |
| SCHEMBL16014767 | 0.86 | TRPA1 (0.36) | TRPA1GCKMALT1TRPV1KCNH2 | |
| SCHEMBL2586280 | 0.84 | MALT1 (0.40) | TRPA1MALT1 | |
| SCHEMBL16014742 | 0.84 | TRPA1 (0.36) | NPC1MAPTNFKB1RAB9ANFKB2 | |
| Fluoride SCHEMBL27807875 | 0.83 | MALT1 (0.39) | TRPA1MALT1 | |
| SCHEMBL29185098 | 0.82 | TRPA1 (0.35) | TRPA1GCKMALT1TRPV1KCNH2 | |
| SCHEMBL27962696 | 0.82 | ALDH1A1 (0.40) | SMN1; SMN2TRPA1GCKMALT1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4376616-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | Syngenta Crop Protection AG (CH) | 2024-06-05 | — | — | EP | disclosed |
| CN-117813006-A | Methods for controlling diamide-resistant pests and compounds thereof | 先正达农作物保护股份公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117715523-A | Methods for controlling diamide-resistant pests and compounds thereof | 先正达农作物保护股份公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2023006634-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-02 | — | — | WO | disclosed |
| US-9609868-B2 | Alkoximino-substituted anthranilic acid diamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20160007603-A1 | ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2016-01-14 | — | — | US | disclosed |
| EP-2964629-A1 | ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014135588-A1 | ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007603-A1 | ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES | ANTXR2, DDT, DAO | NPC1 4830/4885MAPT 4583/4885NFKB1 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.