Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 11/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27944900 | 0.91 | GCK (0.33) | GCKKCNH2TRPA1TRPV1MALT1 | |
| SCHEMBL14658369 | 0.89 | GCK (0.34) | GCKKCNH2TRPA1TRPV1MALT1 | |
| SCHEMBL16014740 | 0.89 | NPC1 (0.37) | GCKKCNH2TRPA1TRPV1MALT1 | |
| SCHEMBL16014767 | 0.84 | TRPA1 (0.36) | GCKKCNH2TRPA1HIF1ATRPV1 | |
| SCHEMBL16014575 | 0.84 | ALDH1A1 (0.39) | GCKKCNH2TRPA1MALT1 | |
| SCHEMBL27944843 | 0.83 | P2RX7 (0.34) | — | |
| SCHEMBL29185079 | 0.83 | TRPA1 (0.35) | GCKKCNH2TRPA1TRPV1MALT1 | |
| SCHEMBL27962696 | 0.81 | ALDH1A1 (0.40) | GCKTRPA1TRPV1MALT1KMT2A | |
| SCHEMBL16014505 | 0.81 | NPC1 (0.40) | GCKKCNH2TRPA1HIF1A | |
| SCHEMBL14658366 | 0.80 | TRPA1 (0.36) | TRPA1HIF1ATRPV1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130769-B | 3-difluoro ethoxy-pyrazole amides compounds and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2014-12-17 | — | — | CN | disclosed |
| CN-103420975-A | Fluorine-contained o-amino thiobenzamide type compound and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2013-12-04 | — | — | CN | disclosed |
| CN-103130769-A | 3-difluoro ethoxy-pyrazole amides compounds and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2013-06-05 | — | — | CN | disclosed |