Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CD40 | P25942 | 1/20 | 0.46 |
| ▸ | CD40LG | P29965 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19882660 | 0.90 | ENPP2 (0.57) | PRMT3EP300PRMT6PRMT1ENPP2 | |
| SCHEMBL6124913 | 0.86 | ENPP2 (0.59) | PRMT3EP300PRMT6PRMT1ENPP2 | |
| SCHEMBL19958022 | 0.84 | ENPP2 (0.54) | PRMT3EP300PRMT6PRMT1ENPP2 | |
| SCHEMBL30843979 | 0.81 | PRMT1 (0.64) | PRMT3EP300PRMT6PRMT1ENPP2 | |
| SCHEMBL27881448 | 0.80 | CASP6 (0.52) | PRMT3EP300PRMT6PRMT1ENPP2 | |
| SCHEMBL7537836 | 0.79 | ENPP2 (0.48) | PRMT3EP300PRMT6PRMT1ENPP2 | |
| SCHEMBL14418338 | 0.78 | ENPP2 (0.55) | PRMT3EP300PRMT6PRMT1ENPP2 | |
| SCHEMBL13388967 | 0.78 | ENPP2 (0.47) | ENPP2CD40CD40LGCA2SUMO2 | |
| SCHEMBL7537842 | 0.78 | ENPP2 (0.49) | PRMT3EP300PRMT6PRMT1ENPP2 | |
| SCHEMBL11069849 | 0.77 | NPC1 (0.54) | PRMT3EP300PRMT6PRMT1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828976-B2 | Identification and use of compounds that affect the fidelity of eukaryotic translation initiation codon selection | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-09-09 | — | — | US | disclosed |