SCHEMBL7537836

SCHEMBL7537836

CNc1ccc(/N=N/c2ccc3c(S(=O)(=O)O)cc(S(=O)(=O)O)cc3c2)cc1.[NaH].[NaH]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 8/20 0.48
CD40 P25942 1/20 0.47
CD40LG P29965 1/20 0.47
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
SUMO2 P61956 1/20 0.44
SUMO1 P63165 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP2 Q9HC62 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
PRMT1 Q99873 2/20 0.43
PRMT3 O60678 1/20 0.43
EP300 Q09472 1/20 0.43
PRMT6 Q96LA8 1/20 0.43
PTPN11 Q06124 2/20 0.41
PTPRC P08575 1/20 0.41
ALOX15 P16050 1/20 0.41
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7537842 0.99 ENPP2 (0.49) ENPP2CD40CD40LGCA12CA2
SCHEMBL11149987 0.87 PRMT1 (0.49) ENPP2CD40CD40LGCA12CA2
SCHEMBL3831401 0.86 PRMT1 (0.58) ENPP2CD40CD40LGCA12CA2
SCHEMBL11154841 0.85 PRMT1 (0.50) ENPP2CD40CD40LGCA12CA2
SCHEMBL7537839 0.80 CA12 (0.49) ENPP2CD40CD40LGCA12CA2
SCHEMBL16015489 0.79 PRMT3 (0.54) ENPP2CD40CD40LGCA2SUMO2
SCHEMBL19882660 0.79 ENPP2 (0.57) ENPP2CD40CD40LGSUMO2SUMO1
SCHEMBL27100629 0.77 CD40 (0.68) ENPP2CD40CD40LGCA2SUMO2
SCHEMBL14647842 0.77 CD40 (0.68) ENPP2CD40CD40LGCA2SUMO2
SCHEMBL13818469 0.77 CASP6 (0.54) ENPP2CA12CA2SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002024816-A1 ROTAXANE DYES BASF AKTIENGESELLSCHAFT (DE) 2002-03-28 WO disclosed