Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11967542 | 1.00 | LMNA (0.35) | LMNATSHRMETMAPTATM | |
| SCHEMBL15827867 | 1.00 | LMNA (0.35) | LMNATSHRMETMAPTATM | |
| SCHEMBL11967540 | 1.00 | LMNA (0.35) | LMNATSHRMETMAPTATM | |
| SCHEMBL15416408 | 0.81 | LMNA (0.36) | LMNATSHRMETMAPTHSD17B10 | |
| SCHEMBL25399244 | 0.78 | — | — | |
| SCHEMBL641967 | 0.77 | TSHR (0.40) | LMNATSHRMETMAPTATM | |
| SCHEMBL4613762 | 0.77 | TSHR (0.40) | LMNATSHRMETMAPTATM | |
| SCHEMBL9891 | 0.77 | TSHR (0.40) | LMNATSHRMETMAPTATM | |
| SCHEMBL7572979 | 0.74 | OPRM1 (0.43) | LMNATSHRMETMAPTATM | |
| SCHEMBL3711846 | 0.74 | OPRM1 (0.43) | LMNATSHRMETMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829196-B2 | TRPA1 antagonists | MERCK SHARP & DOHME CORP. (US) | 2014-09-09 | — | — | US | disclosed |