Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 4/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | WRN | Q14191 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18406642 | 0.86 | MGLL (0.36) | PTGS1PTGS2MGLLBLMALDH1A1 | |
| SCHEMBL18406643 | 0.85 | MGLL (0.35) | PTGS1PTGS2MGLLBLMALDH1A1 | |
| SCHEMBL23900539 | 0.78 | MGLL (0.46) | PTGS1PTGS2MGLLBLMALDH1A1 | |
| SCHEMBL23900909 | 0.77 | MGLL (0.44) | PTGS1PTGS2MGLLBLMALDH1A1 | |
| SCHEMBL22399174 | 0.77 | MGLL (0.52) | PTGS1PTGS2MGLLBLMALDH1A1 | |
| SCHEMBL26210982 | 0.76 | BLM (0.33) | MGLLBLMALDH1A1LMNAMAPT | |
| SCHEMBL21320513 | 0.76 | MGLL (0.37) | PTGS1PTGS2KDM4EMGLLBLM | |
| SCHEMBL27394996 | 0.75 | ALDH1A1 (0.35) | BLMALDH1A1CYP2C19HIF1AWRN | |
| SCHEMBL23900609 | 0.75 | BLM (0.42) | PTGS1PTGS2MGLLBLMALDH1A1 | |
| SCHEMBL557257 | 0.74 | KDM4E (0.59) | KDM4EFFAR1CPT2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320954-B1 | DIAGNOSTIC AGENTS SELECTIVE AGAINST METALLOPROTEASES | BRACCO IMAGING SPA (IT) | 2019-09-04 | — | — | EP | disclosed |
| EP-1853605-B1 | INTEGRIN TARGETED SYNTHETIC LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO IMAGING SPA (IT) | 2014-09-10 | — | — | EP | disclosed |