Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18406642 | 0.85 | MGLL (0.36) | MGLLBLMALDH1A1LMNAMAPT | |
| SCHEMBL16016273 | 0.85 | PTGS1 (0.39) | MGLLBLMALDH1A1LMNAMAPT | |
| SCHEMBL23900539 | 0.77 | MGLL (0.46) | MGLLBLMALDH1A1LMNAMAPT | |
| SCHEMBL23900909 | 0.76 | MGLL (0.44) | MGLLBLMALDH1A1LMNAMAPT | |
| SCHEMBL22399174 | 0.75 | MGLL (0.52) | MGLLBLMALDH1A1LMNAMAPT | |
| SCHEMBL11981948 | 0.75 | KDM4E (0.39) | BLMALDH1A1LMNAGMNNTHPO | |
| SCHEMBL21344801 | 0.74 | BLM (0.37) | MGLLBLMALDH1A1LMNAMAPT | |
| SCHEMBL26210982 | 0.74 | BLM (0.33) | MGLLBLMALDH1A1LMNAMAPT | |
| SCHEMBL27394996 | 0.74 | ALDH1A1 (0.35) | BLMALDH1A1WRNHPGDCYP1A2 | |
| SCHEMBL23900609 | 0.73 | BLM (0.42) | MGLLBLMALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325489-B1 | ASYMMETRIC PROCESS FOR THE PREPARATION OF THIENO-INDOLES DERIVATIVES | NERVIANO MEDICAL SCIENCES SRL (IT) | 2019-11-13 | — | — | EP | disclosed |
| WO-2017012924-A1 | ASYMMETRIC PROCESS FOR THE PREPARATION OF THIENO-INDOLES DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2017-01-26 | — | — | WO | disclosed |