SCHEMBL16016758

SCHEMBL16016758

CC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(O[Si](C(C)C)(C(C)C)C(C)C)[C@H]1O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.52
▸ SLC28A2 O43868 1/20 0.52
▸ SLC29A1 Q99808 1/20 0.52
▸ SLC28A3 Q9HAS3 1/20 0.52
▸ P2RY2 P41231 10/20 0.47
▸ P2RY6 Q15077 8/20 0.47
▸ P2RY4 P51582 4/20 0.46
▸ P2RY14 Q15391 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16016760 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL20503160 0.85 DUT (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL20503161 0.85 DUT (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16940283 0.84 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL25966278 0.84 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL26554037 0.84 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL21563023 0.84 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL19399430 0.84 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL14418621 0.83 LMNA (0.40) P2RY2P2RY6P2RY4
SCHEMBL16808980 0.82 SLC28A1 (0.56) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920084-B2 Ionic tags for synthesis of oligoribonucleotides THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2018-03-20 — — US disclosed
US-20140256926-A1 Ionic Tags for Synthesis of Oligoribonucleotides HONG KONG POLYTECHNIC UNIVERSITY (HK) 2014-09-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256926-A1 Ionic Tags for Synthesis of Oligoribonucleotides RNGTT, OSTC, OSGEP SLC28A1 175/4885SLC28A2 93/4885SLC29A1 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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