Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21016021 | 0.86 | DGKA (0.38) | ADRA2AADRA1AMAPTDGKAMEN1 | |
| SCHEMBL10031825 | 0.86 | HTR2C (0.46) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL27631198 | 0.85 | CYP1A2 (0.47) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL16944248 | 0.84 | DGKA (0.41) | MAPTDGKAMEN1KMT2ADNM1 | |
| SCHEMBL2485813 | 0.83 | ADRA2A (0.42) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL16018396 | 0.83 | ADRA2A (0.39) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL17581525 | 0.82 | DGKA (0.44) | MAPTDGKAMEN1KMT2ADNM1 | |
| SCHEMBL21016197 | 0.81 | ADRA2A (0.33) | ADRA2AADRA1AMAPTBLMDGKA | |
| SCHEMBL16017798 | 0.80 | ADRA2A (0.37) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL8832710 | 0.80 | ADRA2A (0.43) | ADRA2AADRA1AMAPTBLMHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256694-A1 | STEROID ANTIBIOTIC CONJUGATES | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256666-A1 | ANTIBIOTIC CONJUGATES WITH NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256660-A1 | ANTIBIOTIC CONJUGATES LINKED WITH STEROID DRUGS | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256651-A1 | Cyclosporine A steroid conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256696-A1 | Steroid conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256658-A1 | Antibiotic Conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256666-A1 | ANTIBIOTIC CONJUGATES WITH NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | MMP17, NAALAD2, DNPEP | ADRA2A 4765/4885ADRA1A 4558/4885MAPT 3276/4885 |
| US-20140256694-A1 | STEROID ANTIBIOTIC CONJUGATES | CYP17A1, CYP21A2, HSD17B1 | ADRA2A 4204/4885ADRA1A 3020/4885MAPT 3434/4885 |
| US-20140256660-A1 | ANTIBIOTIC CONJUGATES LINKED WITH STEROID DRUGS | CYP21A2, CYP17A1, CYP46A1 | ADRA2A 4577/4885ADRA1A 3774/4885MAPT 3692/4885 |
| US-20140256658-A1 | Antibiotic Conjugates | NAALAD2, DNPEP, ENGASE | ADRA2A 4665/4885ADRA1A 4225/4885MAPT 2636/4885 |
| US-20140256696-A1 | Steroid conjugates | CYP21A2, CYP17A1, HSD17B2 | ADRA2A 2246/4885ADRA1A 1342/4885MAPT 2769/4885 |
| US-20140256651-A1 | Cyclosporine A steroid conjugates | CYP21A2, CHP1, CYP51A1 | ADRA2A 2407/4885ADRA1A 1692/4885MAPT 4019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.