Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354045 | 0.93 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1245257 | 0.93 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL14264450 | 0.89 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL15599734 | 0.85 | L3MBTL1 (0.59) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL6842063 | 0.83 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL15894216 | 0.83 | RAB9A (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1245251 | 0.83 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL22207363 | 0.83 | TP53 (0.45) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL22207162 | 0.83 | RAB9A (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL19901679 | 0.83 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170040548-A1 | DIPHENYLIMIDAZOLE-FUSED, SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2017-02-09 | — | — | US | disclosed |
| US-20170040547-A1 | SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2017-02-09 | — | — | US | disclosed |
| US-9502664-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2016-11-22 | — | — | US | disclosed |
| US-9502664-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2016-11-22 | — | — | US | disclosed |
| EP-2776443-B1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20140252280-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20140252280-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170040547-A1 | SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | SLCO2B1, SLCO4C1, SLCO1B1 | NPC1 284/4885RAB9A 767/4885MEN1 4396/4885 |
| US-20170040548-A1 | DIPHENYLIMIDAZOLE-FUSED, SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | SLCO4C1, SLCO2B1, SLCO1B1 | NPC1 215/4885RAB9A 1388/4885MEN1 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.