Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974237 | 1.00 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1245251 | 1.00 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4210497 | 0.96 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL29973207 | 0.96 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4210533 | 0.91 | KDM4E (0.44) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL29354045 | 0.89 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1245257 | 0.89 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4209528 | 0.87 | ESR2 (0.43) | MEN1KMT2AMAPTTDP1TP53 | |
| SCHEMBL16019276 | 0.83 | NPC1 (0.44) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4207319 | 0.82 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204585-A1 | Process for making triazine UV absorbers using lewis acids and reaction promoters | GUPTA RAM B (US) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204585-A1 | Process for making triazine UV absorbers using lewis acids and reaction promoters | TYR, TDO2, CYP4Z1 | NPC1 2663/4885RAB9A 3193/4885MEN1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.