Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962687 | 0.84 | ALDH1A1 (0.46) | MAPK1HTTALDH1A1LMNA | |
| SCHEMBL16019382 | 0.84 | ALDH1A1 (0.46) | MAPK1HTTALDH1A1LMNA | |
| SCHEMBL7962617 | 0.82 | ALDH1A1 (0.41) | MAPK1HTTALDH1A1 | |
| SCHEMBL16021172 | 0.82 | ALDH1A1 (0.39) | MAPK1HTTALDH1A1PTGS2 | |
| SCHEMBL7976409 | 0.81 | ALDH1A1 (0.35) | MAPK1HTTALDH1A1KDM4E | |
| SCHEMBL7976218 | 0.78 | PRKAB2 (0.37) | MAPK1ALDH1A1LMNA | |
| SCHEMBL1038478 | 0.77 | ALDH1A1 (0.36) | MAPK1HTTALDH1A1 | |
| SCHEMBL9375326 | 0.76 | TSHR (0.47) | ALDH1A1KDM4E | |
| SCHEMBL27841903 | 0.74 | PTGS2 (0.32) | ALDH1A1LMNAKDM4EPTGS2 | |
| SCHEMBL7972601 | 0.73 | ALDH1A1 (0.49) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | PRDX6, PRDX1, CBR3 | MAPK1 1853/4885HTT 3989/4885ALDH1A1 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.